Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
The present study indicated that LRIG2 and LMO7 may be useful prognostic markers in VSCC, particularly for patients without HPV‑driven tumors or with advanced tumors at diagnosis.
|
31059071 |
2019 |
Neoplasms
|
0.030 |
GeneticVariation
|
group |
BEFREE |
The LMO7-BRAF fusion was a recurrent somatic alteration with a frequency of 2.0% (3/148) in PTC tumors, while the BRAF<sup>V600E</sup> point mutation was found in 63.5% (94/148) of tumors.
|
29768105 |
2018 |
Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
LMO7 immunoreactivity was shown to be a negative prognostic factor in LRIG1 positive tumors, predicting poor patient survival.
|
30429017 |
2018 |
Cardiomyopathy, Dilated
|
0.010 |
Biomarker
|
group |
BEFREE |
Association of LIM Domain 7 Gene Polymorphisms and Plasma Levels of LIM Domain 7 with Dilated Cardiomyopathy in a Chinese Population.
|
27988857 |
2017 |
Myopathy
|
0.010 |
GeneticVariation
|
group |
BEFREE |
We identified clusters of misexpressed genes and examined the nuclear positioning of two such genomic clusters, each harboring genes relevant to striated muscle disease including LMO7 and MBNL2.
|
21179469 |
2010 |
Vascular Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
We use carotid ligation and femoral artery denudation models in mice with global or inducible smooth muscle-specific deletion of LMO7, and knockout, knockdown, overexpression, and mutagenesis approaches in mouse and human SMC, and human arteriovenous fistula and cardiac allograft vasculopathy samples to assess the role of LMO7 in neointima and fibrosis.
|
30586711 |
2019 |
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Red Blood Cell Count measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Tonometry
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma.
|
30054594 |
2018 |
Tonometry
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma.
|
29785010 |
2018 |
Tonometry
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association analyses identify new loci influencing intraocular pressure.
|
29617998 |
2018 |
Finding of Mean Corpuscular Hemoglobin
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Arteriovenous fistula
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
We use carotid ligation and femoral artery denudation models in mice with global or inducible smooth muscle-specific deletion of LMO7, and knockout, knockdown, overexpression, and mutagenesis approaches in mouse and human SMC, and human arteriovenous fistula and cardiac allograft vasculopathy samples to assess the role of LMO7 in neointima and fibrosis.
|
30586711 |
2019 |
Colorectal Carcinoma
|
0.300 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|
Bipolar Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
|
29064472 |
2017 |
Diabetes Mellitus, Insulin-Dependent
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.
|
21980299 |
2011 |
Diabetes Mellitus, Insulin-Dependent
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.
|
21980299 |
2011 |
Diabetic Retinopathy
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association study in a Chinese population with diabetic retinopathy.
|
23562823 |
2013 |
Glaucoma, Open-Angle
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma.
|
29449654 |
2018 |
Schizoaffective Disorder
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
|
29064472 |
2017 |
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
|
29064472 |
2017 |
Muscular Dystrophy, Emery-Dreifuss
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
LMO7 (LIM domain only 7) is a transcription regulator for expression of many Emery-Dreifuss muscular dystrophy-relevant genes, and binds to α-actinin and AF6/afadin at adherens junctions for epithelial cell-cell adhesion.
|
29158164 |
2018 |
Muscular Dystrophy, Emery-Dreifuss
|
0.030 |
Biomarker
|
disease |
BEFREE |
To test this, we analyzed RNA-Seq datasets, finding novel isoforms or isoform tissue-specificity for: Lap2, linked to cardiomyopathy; Nesprin 2, linked to Emery-Dreifuss muscular dystrophy and Lmo7, that regulates the Emery-Dreifuss muscular dystrophy linked emerin gene.
|
29912636 |
2018 |
Muscular Dystrophy, Emery-Dreifuss
|
0.030 |
Biomarker
|
disease |
BEFREE |
These findings demonstrate that loss of Lmo7 in mice causes myopathic phenotypes similar to those seen in other EDMD mouse models.
|
24825363 |
2015 |
Malignant neoplasm of lung
|
0.020 |
Biomarker
|
disease |
BEFREE |
The miR-96-LMO7 axis may be a therapeutic target for lung cancer patients, and new diagnostic or therapeutic strategies could be developed by targeting the miR-96-LMO7 axis.
|
28026121 |
2017 |